Topic 197

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33 items. Top items listed below.

PAC-mediated AKI protection is critically mediated but does not exclusively depend on cell-derived microvesicles 197 10

PAC-mediated AKI protection is critically mediated but does not exclusively depend on cell-derived microvesicles 197 10

The PD-L1/PD-1 Axis Blocks Neutrophil Cytotoxicity In Cancer 197 27 14 10 3

Group I p21-activated kinases in leukemia cell adhesion to fibronectin 197 102 3

ST6GAL1-mediated heterogeneity in sialic acid levels potentiates invasion of breast cancer epithelia 197 14

Ral GTPases promote metastasis by controlling biogenesis and organ colonization of exosomes 197 14 3


The superoxide dismutase mimetic GC4419 enhances tumor killing when combined with stereotactic ablative radiation 197 126 14 10 3

CAR T cell entry into tumor islets is a two-step process dependent on IFNγ and ICAM-1 197 88 14 10 3

To close or to collapse: the role of charges on membrane stability upon pore formation 197 78 8

Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations 197 21 14 5

Augmentation of Antibacterial Activity in Mesenchymal Stromal Cells Through Systems-Level Analysis and CRISPR-mediated Activation of CD14 197 3

Platelet counts predict prognosis in IPF, but are not the main source of pulmonary TGFβ1 197 10 3

Parabacteroides distasonis insulin B:9-23 epitope mimic stimulates insulin specific T-cells and enhances Type 1 Diabetes in NOD mice 197 101 10 3

Characterization of exosome release and extracellular vesicle-associated miRNAs for human bronchial epithelial cells irradiated with high charge and energy ions 197 74

Robust T-cell signaling triggered on soft polydimethylsiloxane-supported lipid-bilayers 197 18 8

Kallikrein-related peptidase 14 activates zymogens of membrane type matrix metalloproteinases (MT-MMPs) - a CleavEx library-based analysis 197 3

A dynamical extracellular matrix coat regulates moruloid-blastuloid transitions of ovarian cancer spheroids 197 7 3

Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses 197 27 14 10 3

Rapid growth and fusion of protocells in surface-adhered membrane networks 197 78 8

Mouse thy1-positive spermatogonia suppress the proliferation of spermatogonial stem cells by Extracellular vesicles in vitro 197 57 20 3

A non-canonical DNA damage checkpoint response in a major fungal pathogen 197 46 3

Priming of MSCs with inflammation-relevant signals affects extracellular vesicle biogenesis, surface markers, and modulation of T cell subsets 110 10 3

Severe murine schistosomiasis results from disruption of the modulation of anti-egg CD4 T cell response by immunodominance of a single egg epitope 197 88 27 10

Study of Staphylococcus aureus Biofilm Ability to Destroy Bone Matrix in Absences of Host 197 12 10

Arp2/3 complex-mediated actin assembly drives microtubule-independent motility and phagocytosis in the evolutionarily divergent amoeba Naegleria 197 55 34

Epithelial HVEM promotes basement membrane synthesis and intraepithelial T cell survival and migration 197 88 27 3

Radiation induced toxicity in rectal epithelial stem cell contributes to acute radiation injury in rectum 197 57 10

Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guerin Effects in Lung Epithelial Cells. 197 27 10 3

Unambiguous observation of vesicle fusion in the interior of a cone 197 127 8

Antinociceptive modulation by the adhesion-GPCR CIRL promotes mechanosensory signal discrimination 197 11 3

Lipopolysaccharide administration alters extracellular vesicles in human lung-cancer cells and mice 10 3

PQS-Induced Outer Membrane Vesicles Enhance Biofilm Dispersion in Pseudomonas aeruginosa 52 12 10 3

Expression of Tim-3 drives naive Treg to an effector-like state with enhanced suppressive activity 88 27 14 10 3

PD-L1 lncRNA splice promotes lung adenocarcinoma progression via enhancing c-Myc activity 108 14 10 3

Anti-androgens induce Rab11a-exosome secretion in prostate cancer by suppressing amino acid-sensitive PAT4-mTORC1 signalling 108 14 10 3

Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses 88 27 10 3

Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression 126 14 10 3

Multiplexed 129Xe HyperCEST MRI detection of genetically-reconstituted bacterial protein nanoparticles in human cancer cells. 197 18

Endothelial cells promote productive HIV infection of resting CD4+ T cells by an integrin-mediated cell adhesion-dependent mechanism 27 3

NK cells acquire PD-1 from the membrane of tumor cells. 7 3

P4HA2 is associated with prognosis, promotes proliferation, invasion, migration and EMT in glioma 98 14 3

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors 14 10 3

Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche 98 14 3

Tumor-specific EphA2 receptor tyrosine kinase inhibits anti-tumor immunity by recruiting suppressive myeloid populations in NSCLC 14 10 3

Multi-organ signaling mobilizes tumor-associated erythroid cells expressing immune checkpoint molecules 14 10 3

Curvature effect of PE-included membrane on the behavior of cinnamycin on the membrane 197 8

Staphylococcus aureus secretes immunomodulatory RNA and DNA via membrane vesicles 150 27 3

T cells expanded from renal cell carcinoma are tumor-reactive but fail to produce IFN-γ, TNF-α or IL-2 88 27 10 3

Circulating Clonally Expanded T Cells Reflect Functions of Tumor Infiltrating T Cells 173 88 14 9 3

Role of neutrophil extracellular traps in regulation of lung cancer invasion and metastasis: Structural Insights from a Computational Model 14 10 3

Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2 44 1

TNFRSF14 (HVEM) is a novel immune checkpoint blockade that can be targeted by a monoclonal antibody to improve anti-tumor immunity in humanized mice 126 14 10 3

Abl kinase deficiency promotes AKT pathway activation and prostate cancer progression and metastasis 108 14 10 3

Intravital imaging reveals cell cycle-dependent satellite cell migration during muscle regeneration. 102 3

Epigenetic downregulation of HER2 during EMT leads to tumor resistance to HER2-targeted therapies in breast cancer 98 14 10 3

Pre-existing intratumoral CD8 T cells substantially contribute to control tumors following therapeutic anti-CD40 and polyI:C based vaccination 88 14 10 3

SMPD3-mediated extracellular vesicle biogenesis inhibits oligodendroglioma growth 14 3

Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles 54 3

Peptide:MHC dependent activation of natural killer cells through KIR2DS2 generates anti-tumor responses 88 14 10 3

Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum 98 14 9 4

Involvement of I-BAR protein IRSp53 in tumor cell growth via extracellular microvesicle secretion 108 102 14 3

Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth 14 10 3

Tasmanian devil facial tumour-derived extracellular vesicles reveal mesenchymal transition markers and adhesion molecules related to metastasis. 98 14 3

Cyclic pentapeptide cRGDfK enhances the inhibitory effect of sunitinib on TGF-β1-induced epithelial-to-mesenchymal transition in human non-small cell lung cancer cells 98 14 10 3

The transcriptional landscape of a hepatoma cell line grown on scaffolds of extracellular matrix proteins 57 9 3

HSATII RNA is induced via a non-canonical ATM-regulated DNA-damage response pathway and facilitates tumor cell proliferation and movement 108 14 3

Characterizing microRNA-mediated modulation of gene expression noise and its effect on synthetic gene circuits 74 38 9

Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10 27 3

Adhesion to type I collagen fibrous gels induces E- to N- cadherin switching without other EMT-related phenotypes in lung carcinoma cell A549 98 57 3

The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the microbiome-host interaction. 98 10

Topoisomerase 3B (TOP3B) DNA and RNA Cleavage Complexes and Pathway to Repair TOP3B-linked RNA and DNA Breaks 197 3

LAG3 is a Central Regulator of NK Cell Cytokine Production 27 10 3

NFATc acts as a non-canonical phenotypic stability factor for a hybrid epithelial/mesenchymal phenotype 98 14 3

Brucella suppress innate immunity by down-regulating STING expression in macrophages 174 27 3

Mechanosensitive calcium signaling in filopodia 55 3

IL-4 receptor targeting as an effective immunotherapy against triple-negative breast cancer 126 14 10 3

ELP-dependent expression of MCL1 promotes resistance to EGFR inhibition in triple-negative breast cancer cells 108 14 3

Machine learning-based investigation of the cancer protein secretory pathway 112 14 9 4

Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption 128 34 3

Dynamin-like proteins are essential for vesicle biogenesis in Mycobacterium tuberculosis. 79 12 3

Short chain fatty acid butyrate promotes virus infection by repressing interferon stimulated genes 27 10 3

Chemogenetic activation of astrocytes in the hippocampus and cortex changes the transcriptome of microglia and other cell types. 120 11 3

Ex vivo Immune Profiling in Patient Blood enables Quantification of innate immune Effector Functions 27 10

GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery 3

Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function 88 27 10 3

Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy 14 10 9

Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer Progression 110 108 14 10 3

SUMOylation regulates protein cargo in Astrocyte-derived small extracellular vesicles 34 3

Oncogene Regulated Release of Extracellular Vesicles 108 14 3

The multiplicity of infection does not affect interactions between Cryptococcus neoformans and macrophages 27 10 3

Blocking of EGFR Signaling is a Latent Strategy for the Improvement of Prognosis of HPV Induced Cancer 14 10 3

Enhanced cohesion promotes chromosome stability and limits acquired drug resistance in non small cell lung cancer 14 10 3

Regulatory T cell activation triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses 150 27 3

The Primary Tumor Immune Microenviornment Status Predicts the Response to Immunotherapy and Overall Survival in Breast Cancer 14 10 9

Antiviral effects of miRNAs in extracellular vesicles against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and mutations in SARS-CoV-2 RNA virus 73 1

Salmonella enterica serovar Typhimurium SPI-1 and SPI-2 shape the transcriptional landscape of epithelial cells in a human intestinal organoid model system 114 27 3

TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway 98 14 3

Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model 186 14 10 3

Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome 14 10 3