Topic 11

neurons neuroscience synaptic neuronal excitatory neuron synapses brain mice circuits inhibitory circuit cortex plasticity mouse hippocampal cortical activity interneurons pyramidal nucleus inputs sensory synapse firing postsynaptic inhibition disorders function deficits behavioral receptors presynaptic dendritic gabaergic adult receptor nervous behavior excitability motor behaviors hippocampus calcium glutamatergic optogenetic neural vivo expressing glutamate dependent memory input axonal axons signaling dopamine layer activation release axon projection projections mechanisms slices stimulation channels dendrites central ca1 parvalbumin recordings induced lateral interneuron transmission spontaneous role ca2 currents ventral circuitry dopaminergic potentiation gaba dorsal output here neurotransmission action drosophila alterations postnatal evoked electrophysiological striatal dysfunction connectivity unknown spine

1596 items. Top items listed below.

Hypomyelination leads to alterations in inhibitory function and parvalbumin-positive neuron density in auditory cortex 104 11 2

A critical role for trkB signaling in the adult function of parvalbumin interneurons and prefrontal network dynamics 104 11 2

Reduced dopamine signaling impacts pyramidal neuron excitability in mouse motor cortex 11 2

Deletion of the mitochondrial matrix protein cyclophilin-D prevents parvalbumin interneuron dysfunction and cognitive deficits in a mouse model of NMDA hypofunction 104 11 3 2

Bidirectional regulation of cognitive and anxiety-like behaviors by dentate gyrus mossy cells in male and female mice 56 11 2

Syngap1 Dynamically Regulates the Fine-Scale Reorganization of Cortical Circuits in Response to Sensory Experience 77 11 2

Circadian modulation of neurons and astrocytes controls synaptic plasticity in hippocampal area CA1 77 11 2

A Circuit Model of Auditory Cortex 104 50 11 2

Learning excitatory-inhibitory neuronal assemblies in recurrent networks 104 50 11 2

Idealized model of the developing visual cortex 50 11 2

Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice 65 11 2

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical circuit assembly 77 11 3 2

N-type calcium channels control GABAergic transmission in brain areas related to fear and anxiety 104 11 2

Reactive Oxygen Species Modulate Activity-Dependent AMPA Receptor Transport in C. elegans 77 11 3

Balance between inhibitory cell types is necessary for flexible frequency switching in adult mouse visual cortex 104 50 11 2

Astrocytic glutamate uptake coordinates experience-dependent, eye-specific refinement in developing visual cortex 104 77 11 2

Altered Expression of Cadherin-8 and Cadherin-11 in Neural Circuit Development: Implications for Autism 65 11 2

A KCNQ2 variant causing Early Onset Epileptic Encephalopathy increases spontaneous network-driven activity and excitability of pyramidal cells in the layer II/III and V of the motor cortex during a limited period of development 11 2

COUP-TFI regulates diameter of the axon initial segment in the mammalian neocortex 11 2

Ablation of STAT3 in Purkinje Cells Reorganizes Cerebellar Synaptic Plasticity in Long-Term Fear Memory Network 77 11 2

Astrocytic modulation of information processing by layer 5 pyramidal neurons of the mouse visual cortex 50 11 7 2

Control of E-S Potentiation at two different sites in the dendro-somatic axis 77 11 2

Coincident glutamatergic depolarizations enhance GABAA receptor-dependent Cl- influx in mature and suppress Cl- efflux in immature neurons 77 11 2

A computational grid-to-place-cell transformation model indicates a synaptic driver of place cell impairment in early-stage Alzheimer's Disease 32 11 2

Network-centered homeostasis through inhibition maintains hippocampal spatial map and cortical circuit function 50 11 2

Postsynaptic serine racemase regulates NMDA receptor function 77 11 3 2

Time course of homeostatic structural plasticity in response to optogenetic stimulation in mouse anterior cingulate cortex 77 11 2

Intraneuronal chloride accumulation via NKCC1 is not essential for hippocampal network development in vivo 11 2

Molecular diversity of glutamatergic and GABAergic synapses from multiplexed fluorescence imaging 77 11 2

A new synuclein-transgenic mouse model for early Parkinson's reveals molecular features of preclinical disease 54 11 9 3

Cell-Type-Specific Decrease of the Intrinsic Excitability of Motor Cortical Pyramidal Neurons in Parkinsonian Mice 11 2

Neuron-class specific responses govern adaptive remodeling of myelination in the neocortex 104 11 2

PKD promotes activity-dependent AMPA receptorendocytosis in hippocampal neurons 77 11 3 2

Developmental PCB exposure disrupts synaptic transmission and connectivity in the rat auditory cortex, independent of its effects on peripheral hearing threshold 11 2

Knock-down of hippocampal DISC1 in immune-challenged mice impairs the prefrontal-hippocampal coupling and the cognitive performance throughout development 11 2

Inhibitory parvalbumin basket cell activity is selectively reduced during hippocampal sharp wave ripples in a mouse model of familial Alzheimer's disease 32 11 2

A network model of the barrel cortex combined with a differentiator detector reproduces features of the behavioral response to single-neuron stimulation. 50 11 2

Changes in excitability properties of ventromedial motor thalamic neurons in 6-OHDA lesioned mice 11 2

Mu-opioids suppress GABAergic synaptic transmission onto orbitofrontal cortex pyramidal neurons with subregional selectivity. 104 11 2

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development 65 11 3 2

Tonic GABAergic activity facilitates dendritic calcium signaling and short-term plasticity 82 11 2

Increased excitation-inhibition balance due to a loss of GABAergic synapses in the serine racemase knockout model of NMDA receptor hypofunction 11 2

Dopaminergic neuromodulation of spike timing dependent plasticity in mature adult rodent and human cortical neurons 77 11 2

Transient developmental increase of prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice 104 11 2

Auditory cortex shapes sound responses in the inferior colliculus. 104 50 11 2

Sleep loss drives brain region- and cell type-specific alterations in ribosome-associated transcripts involved in synaptic plasticity and cellular timekeeping 104 11 2

Subanesthetic ketamine reactivates adult cortical plasticity to restore vision from amblyopia 104 11 2

Distinct Neuronal Populations Contribute to Trace Conditioning and Extinction Learning in the Hippocampal CA1 66 50 11 2

Neuroligin3 Splice Isoforms Shape Mouse Hippocampal Inhibitory Synaptic Function 77 11 3

Structural and functional synaptic plasticity induced by convergent synapse loss requires co-innervation in the Drosophila neuromuscular circuit 77 11 2

Adolescent frontal top-down neurons receive heightened local drive to establish adult attentional behavior in mice 116 50 11 2

IGF-I Governs Cortical Inhibitory Synaptic Plasticity By Astrocyte Activation 77 11 2

Human SYNGAP1 Regulates the Development of Neuronal Activity by Controlling Dendritic and Synaptic Maturation 65 11 3 2

Early postnatal inhibitory circuit development in the mouse medial prefrontal and primary somatosensory cortex 104 11 2

Extracellular matrix supports excitation-inhibition balance in neuronal networks by stabilizing inhibitory synapses 77 11 2

Plasticity in prefrontal cortex induced by coordinated nucleus reuniens and hippocampal synaptic transmission 66 11 2

BDNF/TrkB signaling endosomes mediate long-distance dendritic growth by activating CREB/PI3K-mTOR-dependent translation in neuronal cell bodies. 11 3

Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress 113 11 2

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions 32 11 3

Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior 11 2

Differential inhibition of GABA release from mouse hippocampal interneuron subtypesby the volatile anesthetic isoflurane 104 82 11 2

Transient and layer-specific reduction in neocortical PV inhibition during sensory association learning 104 50 11 2

On the Origin of Ultraslow Spontaneous Na+ Fluctuations in Neurons of the Neonatal Forebrain 11 2

Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP 77 11 2

Structural and Functional Brain-wide Alterations in A350V IQSEC2 Mutant Mice Displaying Autistic-like Behavior 65 11 2

Loss of α7 nicotinic acetylcholine receptors in GABAergic interneurons causes sex-dependent impairments in postnatal neurogenesis and cognitive and social behavior 65 11 2

Developmental Phase Transitions in Spatial Organization of Spontaneous Activity in Postnatal Barrel Cortex Layer 4 11 2

Alterations of specific inhibitory circuits of the prefrontal cortex underlie abnormal network activity in a mouse model of Down syndrome 104 11 2

Mu Opioid Receptor Gene Dosage Influences Reciprocal Social Behaviors and Nucleus Accumbens Microcircuitry 71 11 2

Chemogenetic activation of astrocytes in the hippocampus and cortex changes the transcriptome of microglia and other cell types. 120 11 3

Neural circuit mechanism underlying the feeding controlled by insula-central amygdala pathway 50 11 2

Circuit-specific dendritic development in the piriform cortex 50 11 2

RTP801 Is A Key Modulator For Motor Learning 77 11 2

Modeling the short-term dynamics of in vivo excitatory spike transmission 77 11 2

Chronic chemogenetic activation of forebrain excitatory neurons in postnatal life evokes long-lasting changes in mood-related behavior 11 2

Moderate adolescent chronic intermittent ethanol exposure sex-dependently disrupts synaptic transmission and kappa opioid receptor function in the basolateral amygdala of adult rats 141 71 56 11 2

The impact of interneurons on nonlinear synaptic integration in the neocortex 104 11 2

Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula 71 11 2

Learning prediction error neurons in a canonical interneuron circuit 50 11 2

Glutathione S-transferase Pi (Gstp) Proteins Regulate Neuritogenesis in the Developing Cerebral Cortex 65 11 3 2

Chandelier cell anatomy and function reveal a variably distributed but common signal 50 11 2

Top-down Control of Inhibition Reshapes Neural Dynamics Giving Rise to a Diversity of Computations 50 11 2

Synaptic plasticity induced by differential manipulation of tonic and phasic motoneurons in Drosophila 77 11 2

Pervasive compartment-specific regulation of gene expression during homeostatic synaptic scaling 77 11 9 3

Regulation of Hippocampal Excitatory Synapses by the Zdhhc5 Palmitoyl Acyl Transferase 77 11 3

Activation of somatostatin interneurons by nicotinic modulator Lypd6 enhances plasticity and functional recovery in the adult mouse visual cortex 104 11 2

IGF-1 facilitates extinction of conditioned fear 77 11 2

Activation of group II metabotropic receptors attenuates cortical E-I imbalance in a 15q13.3 microdeletion mouse model 104 11 2

EphA7 Isoforms Differentially Regulate Cortical Dendrite Development 77 11 3 2

TRPM4 conductances in thalamic reticular nucleus neurons generate persistent firing during slow oscillations 11 2

Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells 11 2

Transient coupling between subplate and subgranular layers to L1 neurons before and during the critical period 104 50 11 2

Head Movements Control the Activity of Primary Visual Cortex in a Luminance Dependent Manner 50 11 2

Focused ultrasound excites neurons via mechanosensitive calcium accumulation and ion channel amplification 82 11 2

Extracellular GABA waves regulate coincidence detection in excitatory circuits 11 2

Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses 61 11 3 2

The activity-dependent transcription factor Npas4 regulates IQSEC3 expression in somatostatin interneurons to mediate anxiety-like behavior 104 77 11 3

Age-related alterations in prelimbic cortical neuron Arc expression vary by behavioral state and cortical layer 116 22 2

Targeted millisecond-scale activation of cells using non-invasive Sonogenetics 11 2

Long-range GABAergic inhibition modulates spatiotemporal dynamics of the output neurons in the olfactory bulb 104 50 11 2