Topic 128

ros oxygen reactive species stress plant oxidative antioxidant redox h2o2 arabidopsis plants damage production biology accumulation induced response peroxidase tolerance reduced enzymes scavenging nadph glutathione treatment caused under death resistance increased mitochondrial superoxide responses mutant signaling activate mutants photosynthesis photosynthetic defense involved enzyme generation levels leaves triggered light oxidant thaliana oxidase catalase membrane enhanced mitochondria during oxidation gene stresses resistant sod expression regulated dependent aba concentration transport wild acclimation susceptible acid detoxification impaired drought excess transcription homeostasis arrest leads rbohd metabolism peroxide stomatal genes growth physiological via causes localized pathogen overproduction maintain activated against elevated auxin rogfp2 exogenous several abiotic

86 items. Top items listed below.

Plastid gene expression is required for singlet oxygen-induced chloroplast degradation and cell death 128 16 3

JNK signalling regulates antioxidant responses in neurons 128 11 3

Chloroplast-derived photo-oxidative stress causes changes in H2O2 and EGSH in other subcellular compartments 128 95 16 3

Time-of-day dependent responses of cyanobacterial cellular viability against oxidative stress 128 117 67 16 3

The histidine phosphotransfer AHP4 plays a negative role in Arabidopsis plant response to drought 128 16 3

The SEM-4 transcription factor is required for regulation of the oxidative stress response in Caenorhabditis elegans 128 90 3

The rice bundle sheath produces reactive oxygen species during high light stress via NADPH oxidase 128 117 16 3

Root growth responses to mechanical impedance are regulated by a network of ROS, ethylene and auxin signalling in Arabidopsis. 128 16 3

Non-lethal exposure to H2O2 boosts bacterial survival and evolvability against oxidative stress 128 79 21 12 5

Prolonged disturbance of proteostasis induces cellular senescence via temporal mitochondrial dysfunction and enhanced mitochondrial biogenesis in human fibroblasts 128 95 10 3

Transcription factor TGA2 is essential for UV-B stress tolerance controlling oxidative stress in Arabidopsis 128 16 3

Response patterns and mechanisms of plants to water stress 128 16 5

A metabolomics study of ascorbic acid-induced in situ freezing tolerance in spinach (Spinacia oleracea L.) 128 106 67 16 10

Mitochondrial nucleoid organization and biogenesis of complex I require mTERF18/SHOT1 and ATAD3 in Arabidopsis thaliana. 128 95 16 3

Resolving the dynamics of photosynthetically produced ROS by high-resolution monitoring of chloroplastic EGSH in Arabidopsis 128 117 16

DNA damage and oxidizing conditions activate p53 through differential upstream signaling pathways. 128 46 3

HIF1α stability in hypoxia is not oxidant-initiated but can be tuned by redox regulation of the proteasome 128 95 3

Acibenzolar-S-methyl activates stomatal-based defense systemically in Japanese radish by inducing peroxidase-dependent reactive oxygen species production 128 16 12 10 3

An ABA Synthesis Enzyme Allele OsNCED2 Promotes the Aerobic Adaption in Upland Rice 128 16 3

Molecular characterization of differences between the tomato immune receptors Fls3 and Fls2 128 16 12 3

Phytosphingosine induces systemic acquired resistance through activation of sphingosine kinase 128 16 3

Oxidative stress inducing agents copper and alloxan accelerate cell cycle re-entering of somatic plant cells in the presence of suboptimal exogenous auxin. 128 16 10 3

Plasmodesmata-localized proteins and reactive oxygen species orchestrate light-induced rapid systemic signaling in Arabidopsis 128 16 3

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4 128 14 3

Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana 128 16 3

The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response 128 11 3

A plasma membrane nanoplatform ensures signal specificity during osmotic signaling in plants 128 16 3

Skeletal muscle DNMT3A plays a necessary role in endurance exercise by regulating oxidative capacity of red muscles 128 95 3

Complex effects of pH on ROS from mitochondrial complex II driven complex I reverse electron transport challenge its role in tissue reperfusion injury 128 95 67 3

Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors 128 14 10 9

Expression of tyrosine hydroxylase gene from rat leads to oxidative stress in potato plants. 128 16

Endoplasmic Reticulum Associated Degradation (ERAD) Deficiency Promotes Mitochondrial Dysfunction and Transcriptional Rewiring in Human Hepatic Cells 69 3

Aquaporin mediating stomatal closure is associated with water conservation under mild water deficit 128 106 16

Iodoacetic acid disrupts mouse oocyte maturation by inducing oxidative stress and spindle abnormalities 128 10 3

Cadmium interference with iron sensing reveals transcriptional programs sensitive and insensitive to reactive oxygen species 7 3

Polyphosphate Functions In Vivo as Iron Chelator and Fenton Inhibitor 128 79 12 3

Telomerase inhibition causes premature senescence of fetal guinea pig muscle cells 128 95 10 3

Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveals the effects of multiple oxidation on cellular oxidative stress response 128 67 3

Resveratrol shortens the chronological lifespan of Saccharomyces cerevisiae by a pro-oxidant mechanism 128 67 10 3

An adaptive pre-DNA-damage-response protects genome integrity 128 3

Tomato wall-associated kinase SlWak1 acts in an Fls2- and Fls3-dependent manner to promote apoplastic immune responses to Pseudomonas syringae 128 16 3

The soybean Rhg1 amino acid transporter protein becomes abundant along the SCN penetration path and impacts ROS generation 128 16 3

ECSIT prevents Alzheimer's disease pathology by regulating neuronal mitochondrial ROS and mitophagy 32 10 3

Vitamin D regulation of a SOD1-to-SOD2 antioxidative switch to prevent osteosarcoma transformation 128 95 10 3

RLP23 is required for Arabidopsis immunity against the grey mould pathogen Botrytis cinerea 128 16 12 3

UV radiation increases flavonoid protection but decreased reproduction in Silene littorea 128 106 16 15 5

The Identification of A ROS Responsive Motif that is regulated by snoRNP in Arabidopsis 128 16 3

Disordered peptides impair neutrophil bacterial clearance and enhance tissue damage in septic patients 128 27 10 3

Intra-mitochondrial proteostasis is directly coupled to alpha-synuclein and Amyloid β 1-42 pathology 54 32 3

Auranofin resistance in Toxoplasma gondii decreases the accumulation of reactive oxygen species but does not target parasite thioredoxin reductase 128 12

Adaptive modification of lipid droplets mediated by Plin1 functions in infection-induced pathogenesis in Drosophila 128 27 3

Autophagy induced accumulation of lipids in pgrl1 and pgr5 of Chlamydomonas reinhardtii under high light 128 67 16 3

Unraveling Oxidative Stress Resistance: Molecular Properties Govern Proteome Vulnerability 128 79 12

VAPYRIN attenuates defence by repressing PR gene induction and localized lignin accumulation during arbuscular mycorrhizal symbiosis of Petunia hybrids 128 16 3

MAP Kinase OsMEK2 and OsMPK1 Signaling for Ferroptotic Cell Death in Rice-Magnaporthe oryzae Interactions 128 102 16 3

Pattern-recognition receptors are required for NLR-mediated plant immunity 128 16 3

The lysosomal TRPML1 channel promotes breast cancer survival by supporting mitochondrial function and cellular metabolism 95 14 3

Vegetative nuclear positioning is required for calcium and ROS signaling in Arabidopsis pollen tubes 128 16 3

Photoperiod stress alters the cellular redox status and is associated with an increased peroxidase and decreased catalase activity 128 16 3

Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption 128 34 3

Sclerotinia sclerotiorum hijacks copper from its host for infection 128 114 16 12 3

Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death 95 3

Genetic architecture of oxidative stress tolerance in the fungal wheat pathogen Zymoseptoria tritici 53 5

AfRip3, a RIP3-like kinase, is identified as a key modulator of necroptotic death in Aspergillus fumigatus 128 10 3

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients 128 10 3

GSTU7 affects growth performance and acts as an antagonist of oxidative stress induced by methyl viologen 128 16 3

Antioxidant nanozyme counteracts HIV-1 by modulating intracellular redox potential 128 10 3

Prm2 deficiency triggers a Reactive Oxygen Species (ROS)-mediated destruction cascade during epididymal sperm maturation in mice 128 3

Myocardial matrix material supports a proliferative microenvironment for cardiomyocytes 128 85 57 10 3

Tomato fruit susceptibility to fungal disease can be uncoupled from ripening by suppressing susceptibility factors 128 16 12 3

Developmentally regulated activation of defense allows for rapid inhibition of infectionin age-related resistance to Phytophthora capsici in cucumber fruit 128 16 12 3

Unraveling transcription factor functions through integrative inference of transcriptional networks in Arabidopsis thaliana yields novel regulators involved in reactive oxygen species stress signaling 134 31 16 9 4

IgG-aggregates rapidly up-regulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species. 128 27 3

Impaired expression of chloroplast HSP90C chaperone activates plant defense responses leading to a disease symptom-like phenotype 128 16 3

Different salicylic and jasmonic acids imbalances are involved in the oxidative stress-mediated cell death, induced by fumonisin B1 in maize seedlings with contrasting resistance to Fusarium verticillioides ear rot in the field. 128 106 16 10

Deletion of the mitochondrial matrix protein cyclophilin-D prevents parvalbumin interneuron dysfunction and cognitive deficits in a mouse model of NMDA hypofunction 104 11 3 2

Spike development inhibition in the ftin mutant is associated with multiple phenotypes and regulated by multiple biological pathways 128 16 3

Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of oxygen reactive species 7 3

A mitochondria-targeted antioxidant and a thyroid hormone affect carotenoid ketolase gene expression and bill redness in zebra finches 128 95 67

Copper nanoparticle application enhances plant growth and grain yield in maize under drought stress conditions 106 16 5

Zinc oxide nanoparticles modulate the gene expression of ZnT1 and ZIP8 to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells 128 10 3

Negative effects characterization and comparative transcriptomics elucidation on the lag phase of an industrial S. cerevisiae under the corn stover hydrolysate stress 128 67 3

Reactive Oxygen Species Modulate Activity-Dependent AMPA Receptor Transport in C. elegans 77 11 3

Mitohormesis reprograms macrophage metabolism to enforce tolerance 128 27 3

Effect of high-frequency low-intensity pulsed electric field on protecting SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury via ERK pathway 32 10 3

Temperature-dependent fasciation mutants connect mitochondrial RNA processing to the control of cell proliferation during lateral root morphogenesis 128 16 3

Sterol 14α-demethylase is vital for mitochondrial functions and stress tolerance in Leishmania major 95 67 12 3

Distinct Cellular Strategies Determine Sensitivity to Mild Drought of Arabidopsis Natural Accessions 16 5 3

Thermal cycling protects SH-SY5Y cells against hydrogen peroxide and -amyloid-induced cell injury through stress response mechanisms involving Akt pathway 32 10 3

The adaptive transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress 114 79 12 3

Human INCL fibroblasts display abnormal mitochondrial and lysosomal networks and heightened susceptibility to ROS-induced cell death 95 69 3

Oxidative Stress Responses and Nutrient Starvation in MCHM Treated Saccharomyces cerevisiae 128 67 3

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands 128 95

Oxidised phosphatidylcholines induce multiple functional defects in airway epithelial cells 95 10 3

Reactive oxygen species as important regulators of cell division 106 16

Eukarion-134 attenuates endoplasmic reticulum stress-induced mitochondrial dysfunction in human skeletal muscle cells 95 7 3

Gene Expression Signature and Molecular Mechanism of Redox Homeostasis in Colorectal Cancer 128 67 3

Galectin-1-deficient mice are protected against Trypanosoma cruzi infection through altered neutrophil migration and production of reactive oxygen species and nitric oxide 27 10 3

Ectopic overexpression of abiotic stress-induced rice annexin, OsAnn5 potentiates tolerance to abiotic stresses 128 16 3

Mutation of IDR1 enhances drought tolerance by reducing ROS production and activating ROS scavenging in rice 128 16 3