Topic 166
schistosomiasis mansoni schistosoma drugs drug compounds worms parasite anti parasites neglected schistosome inhibitor compound people schistosomes treatment praziquantel tropical efficacy screening worm countries inhibits million targets inhibitors microbiology parasitic action schistosomula salvage including treated vaccine therapeutics inhibition caused development anthelmintic potent haematobium adult egg selective mass disease host homologues dhodh activity agents could new schistosomals evaluation toxicity identification other resistant flatworm agent pharmacological discovery activities target mg death lifecycle multidrug demonstrated interventions poorest ec50 inhibited overexpression antibiotic profiling tested liver active circulation uridine molecule infection trials induced into methanolic against highly 68 methodology pyrimidine novel concentrations selectivity lactone pzq venom
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