Topic 133

neurogenesis progenitor neurons progenitors neuronal radial differentiation developing developmental glial neural cortex cortical fate neurogenic brain glia mouse development regulates cells neuroscience transcription oligodendrocyte specification stem lineage factor neuron cerebral during signaling generate embryonic cell astrocytes zone subventricular controls nervous opc migration shh identity rgcs regulator maturation telencephalon neocortex factors sonic oligodendrocytes adult mtor switch mammalian opcs glutamatergic generation early role hedgehog regulate precursor proliferation forebrain myelination deletion postnatal neurodevelopmental mice reveals excitatory proper postmitotic competence utero timing neocortical undergo malformations regulatory defined precursors divisions expressed microcephaly ventricular show born tracing impaired chromatin interneuron generated subtype embryos loss rgc expansion

64 items. Top items listed below.

A SMAD1/5-YAP signaling module drives radial glia self-amplification and growth of the developing cerebral cortex 133 20 3

Unraveling the transcriptional networks that drive oligodendrocyte fate specification in Sonic hedgehog-responsive neocortical progenitors 133 20 9 3

In utero gene transfer system for embryos before neural tube closure reveals a role for Hmga2 in the onset of neurogenesis 133 20 3

Heterogeneity of Neuroepithelial Cells and Radial Glia 133 120 20 9

p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis 133 20 3

The transcription factor ZEB1 regulates stem cell self-renewal and astroglial fate in the adult hippocampus 133 20 11 3

A subpopulation of astrocyte progenitors defined by Sonic hedgehog signaling 133 20 11 3

mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex 133 55 20 11 3

Intrinsic neuronal activity during migration controls the recruitment of specific interneuron subtypes in the postnatal mouse olfactory bulb 133 11 2

A Casz1 - NuRD complex regulates temporal identity transitions in neural progenitors 133 20 3

De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis 133 31 11 3 2

Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis 133 20 11 3

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signalling to promote expansion of cortical progenitors. 133 20 11 3

A transient role of primary cilia in controlling direct versus indirect neurogenesis in the developing cerebral cortex 133 20 11 3

Atoh7-independent specification of retinal ganglion cell identity 133 72 20 3

Parallel RNA and DNA analysis after Deep-sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain 133 120 9

The transcription factor CLAMP is required for neurogenesis in Drosophila melanogaster. 192 133 20 3

Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating Shh signaling response 133 20 3

Variation of human neural stem cells generating organizer states in vitro before committing to cortical excitatory or inhibitory neuronal fates 133 57 11 2

The neocortical progenitor specification program is established throughcombined modulation of SHH and FGF signaling 133 20 3

Activation of a neural stem cell transcriptional program in parenchymal astrocytes 133 57 11 3 2

Single cell epigenomic atlas of the developing human brain and organoids 133 120 20 9 3

The npBAF to nBAF Chromatin Switch Regulates Cell Cycle Exit in the Developing Mammalian Cortex 133 20 3

Ephrin-B2 paces neuronal production in the developing neocortex 133 20 11 3

Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. 133 20 3

Pairing your Sox: identification of Sox11 partner proteins and interaction domains in the developing neural plate 133 20 3

mTOR inhibition in primary neurons and the developing brain represses transcription of cholesterol biosynthesis genes and alters cholesterol levels 133 31 3

Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation 133 68 20 11 3

Altered patterning of interneuron progenitors in Down syndrome 133 20 11 3

Foxm1 regulates neuronal progenitor fate during spinal cord regeneration 133 20 3

Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development 133 11 3

Regenerative neurogenic response from glia requires insulin driven neuron-glia communication 133 57 11 3

Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly 133 3

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord 133 20 3

Smoothened receptor Signaling regulates the developmental shift of GABA polarity in rat somatosensory cortex 133 11 3 2

Bone morphogenetic protein signaling regulates Id1 mediated neural stem cell quiescence in the adult zebrafish brain via a phylogenetically conserved enhancer module 133 20 3

Cooperative action of miR-124 and ISX9 in instructing direct reprogramming of mouse astrocytes to induced-neurons in vitro and in vivo 133 74 3

Regulatory interactions between Vax1, Pax6, and miR-7 regionalize the lateral Ventricular-Subventricular Zone during post-natal Olfactory Bulb neurogenesis in mice 133 11 3

Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus 133 20 9 3

Single-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor Cells 133 120 9 3

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas. 133 31 9 3

HIF╬▒ regulates developmental myelination independent of autocrine Wnt signaling 133 20 3

Fezf2 transient expression via modRNA with concurrent SIRT1 inhibition enhances differentiation of cortical subcerebral / corticospinal neuron identity from mES cells 133 57 20 11 3

Canonical Wnt-signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons 133 11 3 2

A dendritic-like microtubule network is organized from swellings of the basal fiber in neural progenitors 133 34 20 11 3

Mitochondria dynamics in postmitotic cells drives neurogenesis through Sirtuin-dependent chromatin remodeling. 133 20 11 3 2

Regulation of retinal neurogenesis by somatostatin signaling. 72 20 3

Population dynamics and neuronal polyploidy in the developing neocortex 169 7

Single-cell transcriptomic analysis identifies neocortical developmental differences between human and mouse 120 43 9 3

Lis1 mutation prevents basal radial glia-like cell production in the mouse 133 20 3

Subventricular zone adult mouse neural stem cells and human glioblastoma stem cells require insulin receptor for self-renewal 133 108 3

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding 133 20 3

Evidence of progenitor cell lineage rerouting in the adult mouse hippocampus 133 11 10 3

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical circuit assembly 77 11 3 2

Activation of endogenous retroviruses during brain development causes neuroinflammation 133 11 3

TET1-DNA Hydroxymethylation Mediated Oligodendrocyte Homeostasis is Required for CNS Myelination and Remyelination 133 20 3

Astrocytes and neurons share brain region-specific transcriptional signatures 116 11 9 3 2

Enhanced FGFR3 activity in post-mitotic principal neurons during brain development results in cortical dysplasia and axon miswiring 133 11 3

Notch Signaling Commits Mesoderm to the Cardiac Lineage 20 3

CRL5-dependent regulation of Arl4c and Arf6 controls hippocampal morphogenesis. 133 34 20 11 3

An unconventional cerebrospinal fluid-derived Semaphorin-signalling regulates apical progenitor dynamics in the developing neocortex 133 20 11 3

Docosahexaenoic acid has stem cell-specific effects in the SVZ and restores olfactory neurogenesis and function in the aging brain 57 3

Atypical neurogenesis in induced pluripotent stem cell (iPSC) from autistic individuals 57 20 11 9 3 2

Asymmetric neurogenic commitment of retinal progenitors is regulated via the Notch endocytic pathway 7 3

Olig3 acts as a master regulator of cerebellar development 133 11 3

Dissecting Hes-centered transcriptional networks in neural stem cell maintenance and tumorigenesis in Drosophila 20 3

Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures 57 20 9 3

Enteric glia as a source of neural progenitors in adult zebrafish 57 20 11 3

COUP-TFI regulates diameter of the axon initial segment in the mammalian neocortex 11 2

TCF7L2 regulates postmitotic differentiation programs and excitability patterns in the thalamus 133 11 3

Intrauterine growth restriction causes cellular, molecular, and behavioral deficits consistent with abnormal dentate gyrus neurogenesis in mice 168 65 11 3 2

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation 31 20 3

Single-cell Sequencing Reveals Brain/Spinal Cord Oligodendrocyte Precursor Heterogeneity and Requirement for mTOR in Cholesterol Biosynthesis and Myelin Maintenance 133 120 20 11 3

Akt is required for artery formation during embryonic vascular development 94 20 3

An early cortical progenitor-specific mechanism regulates thalamocortical innervation 133 11 3 2

Differentiation of ciliated human midbrain-derived LUHMES neurons 57 20 3

The transcription factor Pou3f1 provides a new map to the glutamatergic neurons of the cerebellar nuclei 133 120 20 9 3

The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses 133 118 20 11 3

Cortical Organoids Model Early Brain Development Disrupted by 16p11.2 Copy Number Variants in Autism 65 11 2

High resolution mouse subventricular zone stem cell niche transcriptomereveals features of lineage, anatomy, and aging 120 57 9

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development 65 11 3 2

Chemogenetic activation of astrocytes in the hippocampus and cortex changes the transcriptome of microglia and other cell types. 120 11 3

Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation. 43 20 9 3

Cell-type specific impact of glucocorticoid receptor activation on the developing brain 168 65 57 11 9 3

Quantitative trait locus mapping identifies Col4a6 as a novel regulator of striatal dopamine level and axonal branching in mice. 9

Human microglia upregulate cytokine signatures and accelerate maturation of neural networks 57 20 9 3

Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development 118 20 3

Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders 65 9 3

Interspecies Chimeric Conditions Affect the Developmental Rate of Human Pluripotent Stem Cells 57 20 9

Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development 120 20 9 3

An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution 118 20 9 3

A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord 118 20 3

Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain. 120 57 9

Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion 186 14 11 3

3D Epigenomic Characterization Reveals Insights Into Gene Regulation and Lineage Specification During Corticogenesis 31 9 3

Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex 116 20 11 9

Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes 133 120 11 3

The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis 168 11 3 2

Genetic influences on cell type specific gene expression and splicing during neurogenesis elucidate regulatory mechanisms of brain traits 9 3

Generation of neuronal diversity from common progenitors via Notch signaling in the cerebellum 20 11 3