Topic 94

endothelial vascular vessel angiogenesis blood vessels vasculature ecs angiogenic formation developmental zebrafish sprouting cells cell flow endothelium ec biology venous shear morphogenesis vegf signaling development extracellular lymphatic regulates regulating arteries migration embryonic loss arterial remodeling essential regulated lumen proliferation cardiovascular matrix growth migrate mediated mouse vein capillary vivo notch during artery regulate mechanistically expression embryos retinal induced impaired capillaries pericytes adult retina barrier regulator junctions lymphangiogenesis actin specification diameter mice junction function required cerebral adhesion microcirculation perfusion proper stress dysfunction fluid integrity resulted factors maturation imaging activation role aortic malformations modulate rescued collagen postnatal inactivation promotes ablation umbilical process aorta

102 items. Top items listed below.

Akt is required for artery formation during embryonic vascular development 94 20 3

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis 94 20 3

Simulating flow induced migration in vascular remodelling 94 38 18

Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity. 94 20 3

An organotypic in vitro model of matured blood vessels 94 85 18

A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina 94 20 3

SMAD6 Integrates Endothelial Cell Homeostatic Flow Responses Downstream of Notch 94 7 3

Excess Centrosomes Disrupt Vascular Lumenization and Endothelial Cell Adherens Junctions 94 7 3

Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks 94 20 3

Fat1 regulates astrocyte maturation and angiogenesis in the retina 94 20 3

Heterogeneity in collective endothelial cell behavior is a driver of arterio-venous remodeling 94 20 3

Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development 94 20 3

The effect of absent blood flow on the zebrafish cerebral and trunk vasculature 94 10 3

Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size 94 55 34 3

VEGFC induced cell cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells 94 20 3

Numerical evaluation reveals the effect of branching morphology on vessel transport properties during angiogenesis 94 3

Distinct Vegfa isoforms control endothelial cell proliferation through PI3 kinase signalling mediated regulation of cdkn1a/p21 94 20 3

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling 94 3

NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin. 94 3

Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning 94 20 3

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish 94 20 3

Nucleolin is expressed in human fetal brain development and reactivated in human glial brain tumors regulating angiogenesis and vascular metabolism 94 14 3

In vitro modeling of tumor spheroid interactions to perfused blood vessels 94 85 57 14 3

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart 94 20 3

Notch Regulates Vascular Collagen IV Basement Membrane Through Modulation of Lysyl Hydroxylase 3 Trafficking 94 7 3

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1 94 20 3

Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways 94 3

Laminin-511 and Alpha 6 Integrins Regulate the Expression of CXCR4to Promote Endothelial Morphogenesis 94 3

A multiscale model of complex endothelial cell dynamics in early angiogenesis 94 38

Reduction of neuronal activity mediated by blood-vessel regression in the brain 94 11 10 3

Dach1 extends artery networks and protects against cardiac injury 94 20 3

CD44 regulates blood-brain barrier integrity in response to fluid shear stress. 94 3

Single-cell RNA-seq reveals endoimmune cells in zebrafish 94 9 3

Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk 94 20 3

p53 plays a central role in lymphatic anomalies 94 3

On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling 94 38

Endothelial Cell Cycle State Determines Propensity for Arterial-Venous Fate 94 20 3

Paladin is a PI(4,5)P2 phosphoinositide phosphatase that regulates endosomal signaling and angiogenesis 94 34 3

Dual function of perivascular fibroblasts in vascular stabilization in zebrafish 94 20 3

Arterial endoglin does not protect against arteriovenous malformations 94 3

Pericytes Directly Communicate with Emerging Endothelial Cells During Vasculogenesis 94 7 3

Cell-ECM interactions play distinct and essential roles at multiple stages during the development of the aortic arch arteries 94 20 3

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote beta cell regeneration 94 3

Notch controls arterialization by regulating the cell cycle and not differentiation 94 20 3

Endothelial Barrier Function is co-regulated at Vessel Bifurcations by Fluid Forces and Sphingosine-1-Phosphate 94 85 3

Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells 94 14 10 3

The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS-mTOR signaling and vascular function 94 3

Vascular-Derived SPARC and SerpinE1 Regulate Interneuron Tangential Migration and Accelerate Functional Maturation of Human Stem Cell-Derived Interneurons 94 57 20 11 10 3

Lnc-ECAL-1 controls cerebrovascular homeostasis by targeting endothelium-specific tight junction protein Cldn5b 94 74 3

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for hemorrhagic dissemination of infection 94 3

Developmental Expression of Transforming Growth Factor Induced Protein Promotes NF-Kappa-B Mediated Angiogenesis During Postnatal Lung Development 94 3

Endothelial TGF-β signaling instructs smooth muscle development in the cardiac outflow tract 94 20 3

DDR2 induces linear invadosome to promote angiogenesis in a fibrillar type I collagen context 94 34 3

Transient high glucose causes delayed wound healing by the DNMT1-mediated Ang-1/NF-κB pathway 168 94 10 3

Vascular Injury Changes Topology of Vessel Network to Adapt to Partition of Blood Flow for New Arteriovenous Specification 94 20 3

Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression 94 3

Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo 94 55 38 18

LPHN2 controls vascular morphogenesis by inhibiting endothelial cell adhesion and YAP/TAZ signaling 94 3

Endothelial CXCL12 regulates neovascularization during tissue repair and tumor progression 94 3

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy 188 94 10 3

Endothelial cell invasiveness is controlled by myosin IIA-dependent inhibition of Arp2/3 activity 94 55 3

A new microcirculation culture method with a self-organized capillary network 94 18

A molecular map of lymph node blood vascular endothelium at single cell resolution 148 94 88 20 3

RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice 94 20 3

A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage 94 10 3

AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fateand controls lymphangiogenesis 94 20 3

Redundant function of Ets1 and Ets2 in regulating M-phase progression in post-natal angiogenesis 94 20 3

Remodeling mechanisms determine size distributions in developing retinal vasculature 94 38

Disrupted Endothelial Cell Heterogeneity and Network Organization Impairs Vascular Function in Prediabetic Obesity 94 10 3

Mechanical Regulation of Microvascular Angiogenesis 94 85 3

The PNUTS-PP1 axis regulates endothelial aging and barrier function via SEMA3B suppression 94 3

Protein tyrosine phosphatase-PEST (PTP-PEST) mediates hypoxia-induced endothelial autophagy and angiogenesis through AMPK activation 94 3

Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence 94 20 3

Mechanical Tension in Syndecan-1 is Regulated by Extracellular Mechanical Cues and Fluidic Shear Stress 94 55 18 3

EHBP1 and EHD2 regulate Dll4 caveolin-mediated endocytosis during blood vessel development 94 34 3

Astrocytes are necessary for blood-brain barrier maintenance in the adult mouse brain 94 3

Integrating Engineered Macro Vessels with Self-assembled Capillaries in 3D Implantable Tissue for Promoting Vascular Integration In-vivo 94 85 18 10

Identification of a novel population of peripheral sensory neuron that regulates blood pressure 94 11 3

Desert Hedgehog-driven endothelium integrity is enhanced by Gas1 but negatively regulated by Cdon 94 10 3

Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction 94 3

Modeling cellular crosstalk and organotypic vasculature development with human iPSC-derived endothelial cells and cardiomyocytes 57 20 3

In Lyl1-/- mice, adipose stem cell vascular niche impairment leads to premature development of fat tissues 39 20 3

Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke 94 10 3

Pre-determined macromolecular leakage sites with dynamic properties establish endothelial intra-vessel heterogeneity 94

The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors 36 1

Cardiovascular disease risk factors induce mesenchymal features and senescence in cardiac endothelial cells 94 3

Hyaluronan-NK cell Interaction Controls the Primary Vascular Barrier during Early Pregnancy 94 20 3

Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain 94 18 4

Mechanistic modeling of vascular tumor growth: an extension of Biot's theory to hierarchical bi-compartment porous medium system 94 85 18

Rapamycin as a potent and selective inhibitor of vascular endothelial growth factor receptor in breast carcinoma 14 10 3

The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors 94 20 3

Increased isoDGR motifs in plasma fibronectin are associated with atherosclerosis through facilitation of vascular fibrosis 94 10 3

Differentiation of human intestinal organoids with endogenous vascular endothelial cells 57 20 9 3


Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosis 94 9 3

Environmental Oxygen Regulates Astrocyte Proliferation to Guide Angiogenesis during Retinal Development 94 20 3

Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins 94

Retina-specific targeting of pericytes reveals structural diversity and enables control of capillary blood flow 94

Alk1 mutant endothelial cells undergo clonal expansion in mouse brain arteriovenous malformations 188 94 10 3

Effects of Post-Myocardial Infarction Heart Failure on the Bone Vascular Niche 57 10 3