Topic 177

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16 items. Top items listed below.

Condensin I subunit Cap-G is essential for proper gene expression during the maturation of post-mitotic neurons 177 6 3

Differences in mitochondrial activity trigger cell competition during early mouse development. 177 6 3

Context-specific functions of Notch in Drosophila blood cell progenitors 177 6 3

Optical TrkB activation in Parvalbumin interneurons regulates intrinsic states to orchestrate cortical plasticity 177 6 3 2

A transient decrease in mitochondrial activity is required to establish the ganglion cell fate in retina adapted for high acuity vision 177 6 3

Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy 177 6 3

Mechanics regulate human embryonic stem cell self-organization to specify mesoderm 177 6 3

A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells 177 6 3

Developmental effects of oxytocin neurons on social affiliation and processing of social information 177 6 2

Multiple pathways of LRRK2-G2019S / Rab10 interaction in dopaminergic neurons 177 6 3

Deep and superficial layers of the primary somatosensory cortex are critical for whisker-based texture discrimination in mice 177 6 2

Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation. 177 6 3

Stress induces cytoprotective TDP-43 nuclear bodies through lncRNA NEAT1-promoted phase separation 177 6 3

Groucho/TLE opposes axial to hypaxial motor neuron development 177 6 3

Improved stability of an engineered function using adapted bacterial strains 6

Anatomy and activity patterns in a multifunctional motor neuron and its surrounding circuitsGOOGLE 177 6 2

Fluorescence-Detected Conformational Changes in Duplex DNA in Open Complex Formation by E. coli RNA Polymerase: Upstream Wrapping and Downstream Bending Precede Clamp Opening and Insertion of the Downstream Duplex 177 6

The nervous system is the major target for Gold nanoparticle: Evidence from RNA sequencing data of C. elegans 6

Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes 6

Proliferation genes repressed by TGF-β are downstream of Slug/Snail2 in normal bronchial epithelial progenitors and are deregulated in COPD 6 3

Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis 6 3

Dataset Augmentation Allows Deep Learning-Based Virtual Screening To Better Generalize To Unseen Target Classes, And Highlight Important Binding Interactions 6 4

Discovery and biosynthesis of clostyrylpyrones from the obligate anaerobe Clostridium roseum 6

Cytoplasmic CPSF6 regulates HIV-1 capsid trafficking and infection in a cyclophilin A-dependent manner 6 3

Comprehensive Transcriptomic Analysis of COVID-19 Blood, Lung, and Airway 6 1

Why do pathway methods work better than they should? 187 6

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses 6 1

Pre-existing cutaneous conditions could increase the risk for SARS-COV-2 infection. 6 1

Age-dependent glycomic response to the 2009 pandemic H1N1 influenza virus and its association with disease severity 6 1

STING Promotes Breast Cancer Cell Survival by an Inflammatory-Independent Nuclear Pathway Enhancing the DNA Damage Response 6 3

An automated, high throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma 6

Notch1 switches progenitor competence in inducing medulloblastoma 6 3

Identification of a Nonsense-Mediated Decay pathway at the Endoplasmic Reticulum 6 3

Label-free three-dimensional observations and quantitative characterisation of on-chip vasculogenesis using optical diffraction tomography 6

Characterization of interstitial heterogeneity in the developing kidney 187 6 3

The influence of peptide context on signalling and trafficking of glucagon-like peptide-1 receptor biased agonists 187 6

Visualization of individual cell division history in complex tissues 6 3

CD45 pre-exclusion from the tips of microvilli establishes a phosphatase-free zone for early TCR triggering 6 3

Regulation of protein abundance in genetically diverse mouse populations 6

Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing 6

The use of hybrid data-dependent and -independent acquisition spectral libraries empower dual-proteome profiling 6

14-3-3ζ mediates an alternative, non- thermogenic mechanism to reduce heat loss and improve cold tolerance 6 3

A Liquid-to-Solid Phase Transition Enhances the Catalytic Activity of SARM1 6 3

Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control 6

Parietal cell-Specific SLC26A9 Deletion induces spontaneous Gastric Carcinogenesis in Mice 6 3

Antimicrobial peptides signal need for sleep from peripheral wounds to the nervous system 6 3

Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes 6

Daily mitochondrial dynamics in cone photoreceptors 6

Combined CTL and NK cell cytotoxicity against cancer cells 6

ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in glioblastoma 6 3

Increasing glucose uptake into neurons antagonizes brain aging and promotes health and life span under dietary restriction in Drosophila 6 3

CUB and Sushi Multiple Domains 1 (CSMD1) opposes the complement cascade in neural tissues 6

The architecture of protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit 6 3

Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells 6 3

Lineage and Spatial Mapping of Glioblastoma-associated Immunity 6 3

Independent apical and basal mechanical systems determine cell and tissue shape in the Drosophila wing disc 6

Localized cell-surface sampling of a secreted factor using cell-targeting beads 6 3

GPR183 regulates interferons and bacterial growth during Mycobacterium tuberculosis infection: interaction with type 2 diabetes and TB disease severity 6 3

Tau in the brain interstitial fluid is fragmented and seeding-competent 6

Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury 6 3

A family of contact-dependent nuclease effectors contain an exchangeable, species-identifying domain 6

Robustness testing and scalability of phosphate regulated promoters useful for two-stage autoinduction in E. coli 6

rec-Y2H matrix screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins 6 3

Anterior thalamic function is required for spatial coding in the subiculum and is necessary for spatial memory 6

Metformin improves cognition of aged mice by promoting cerebral angiogenesis and neurogenesis 6 3

KCNQ gene family members act as both tumor suppressors and oncogenes in gastrointestinal cancers 6 3

Location specific small RNA annealing to the HCV 5' UTR promotes Hepatitis C Virus replication by favoring IRES formation and stimulating virus translation 6

Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland 6 3

A functional screen of translated pancreatic lncRNAs identifies a microprotein-independent role for LINC00261 in endocrine cell differentiation 6 3

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy 6 3

Molecular dynamics reveals complex compensatory effects of ionic strength on the SARS-CoV-2 Spike/hACE-2 interaction 6 1

The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity. 6 2

Neuronal NOX4 knockdown alleviates pathological tau-related alterations in a humanized mouse model of tauopathy 6 3

The spatial structure of feedforward information in mouse primary visual cortex 6 2

Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels 6 3

Mapping of Neuropeptide Y Expression in Octopus Brains 6

Negative controls of chemical probes can be misleading 6

The role of pregnancy-specific glycoproteins on trophoblast motility in three-dimensional gelatin hydrogels 6

Mechano-bactericidal nanopillars require external forces to effectively kill bacteria 187 6

An investigation into the critical role of fibre orientation in the ultimate tensile strength and stiffness of human carotid plaque caps 6

Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis 6 1

High-resolution line-scanning reveals distinct visual response properties across human cortical layers 6 2

Cholesterol metabolism drives regulatory B cell function 6 3

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers 187 6

Degradation of Alzheimers Amyloid-beta by a Catalytically Inactive Insulin Degrading Enzyme 6

ZFP982 confers stem cell characteristics by regulating expression of Nanog, Zfp42 and Dppa3 6 3

Silent cold-sensing neurons drive cold allodynia in neuropathic pain states 6

CELLector: Genomics Guided Selection of Cancer in vitro Models 6 4

SAMHD1 promotes oncogene-induced replication stress 6 3

An active chromatin interactome in relevant cell lines elucidates biological mechanisms at genetic risk loci for dermatological traits 6

Hormonal and neural correlates of care in active versus observing poison frog parents 6 2

Generation of human bronchial organoids for SARS-CoV-2 research 6 1

Niche-derived soluble DLK1 promotes glioma stemness and growth 6 3

Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct 6

Optogenetic activation of heterotrimeric Gi proteins by LOV2GIVe - a rationally engineered modular protein 6

Tau amyloidogenesis begins with a loss of its conformational polymorphism 6 3

Molecularly Targeted Magnetic Resonance Imaging and Spectroscopy 187 6

Quantifying the monomer-dimer equilibrium of tubulin with mass photometry 6

Integrated intra- and intercellular signaling knowledge for multicelullar omics analysis 6

Proposed allosteric inhibitors bind to the ATP site of CK2α 6